СУПЕРСЕМЕЙСТВА ЭФФЛЮКСНЫХ НАСОСОВ PSEUDOMONAS AERUGINOSA (ОБЗОР ЛИТЕРАТУРЫ)

Аннотация

Существенный рост числа антибиотикорезистентных микроорганизмов, отмечаемый в последние годы, является проблемой здравоохранения во всем мире. Одним из молекулярных механизмов формирования устойчивости к антимикробным препаратам (АМП) у бактерий является наличие у них эффлюксных насосов. Приведен анализ экспериментальных работ, связанных с исследованием эффлюксных насосов у клинических штаммов Pseudomonas aeruginosa, одного из представителей госпитальных патогенов группы ESKAPE. Обзор предназначен для специалистов, разрабатывающих новые виды лекарственных средств против антибиотикорезистентных штаммов, научным сотрудникам, изучающим механизмы устойчивости бактерий к АМП, тяжелым металлам, биоцидам и иным противомикробным факторам.

Об авторах

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