РЕТИНОЛ-СВЯЗЫВАЮЩИЙ БЕЛОК 4 И ЕГО РОЛЬ КАК ЛАБОРАТОРНОГО БИОМАРКЕРА ПРИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЯХ (ОБЗОР ЛИТЕРАТУРЫ)
Doi: 10.51620/0869-2084-2024-6 ISSN: 0869-2084 (Print) ISSN: 2412-1320 (Online)
Аннотация
Сердечно-сосудистые заболевания (ССЗ) представляют собой глобальную медицинскую, социальную и экономическую проблему. В настоящее время ведется активный поиск новых биологических маркеров и терапевтических мишеней с целью разработки эффективных подходов к стратификации риска и вторичной профилактике сердечно-сосудистой патологии. Особый интерес исследователей привлекает ретинол-связывающий белок 4 (RBP4). Цель данной статьи – проанализировать
исследования, посвященные роли RBP4 как диагностического и прогностического лабораторного маркера при ССЗ. Согласно
результатам проведенных исследований, RBP4 является молекулой с перспективным диагностическим и прогностическим
потенциалом при ССЗ.
Annotation
Cardiovascular disease (CVD) is a global health, social and economic problem. Currently, there is an active search for new
biological markers and therapeutic targets in order to develop effective approaches to risk stratification and secondary prevention of
cardiovascular pathology. Of particular interest to researchers is retinol binding protein 4 (RBP4). The purpose of this article is to
review studies examining the role of RBP4 as a diagnostic and prognostic laboratory marker in CVD. According to the results of the
studies, RBP4 is a molecule with promising diagnostic and prognostic potential in CVD.
Список литературы
ЛИТЕРАТУРА ( п п . 1 , 2 , 7 — 1 5 , 1 7 — 3 2 , 3 4 — 5 0
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Для цитирования:
Алиева А.М., Байкова И.Е., Рахаев А.М., Котикова И.А., Никитин И.Г. Ретинол-связывающий белок 4 и его роль как лабораторного биомаркера при сердечно-сосудистых заболеваниях (обзор литературы). Клиническая лабораторная диагностика. 2024; 69 (7): 316-323. DOI: https://doi.org/10.51620/0869-2084-2024-69-7-316-323
For citation:
Alieva A.M., Baykova I.E., Rakhaev A.M., Kotikova I.A., Nikitin I.G. Retinol-binding protein 4 as a laboratory biomarker in cardiovascular diseases (review of literature). Klinicheskaya Laboratornaya Diagnostika (Russian Clinical Laboratory Diagnostics). 2024; 69 (7): 316-323 (in Russ.). DOI: https://doi.org/10.51620/0869-2084-
2024-69-7-316-323