МИКРОРНК: РОЛЬ В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ, ПЕРСПЕКТИВЫ КЛИНИЧЕСКОГО ПРИМЕНЕНИЯ

Аннотация

Представлен анализ опубликованных данных о диагностической роли микроРНК при развитии сердечно-сосудистых заболеваний. МикроРНК представляют собой класс малых некодирующих РНК, регулирующих экспрессию генов и влияющих на различные функции клетки. Описаны современные методы исследования микроРНК. Проанализированы данные об изменении их концентрации при ишемической болезни сердца, сердечной недостаточности и других заболеваниях. В настоящее время накопление клинических данных о роли этих биомаркёров позволит определить диагностическую и прогностическую значимость отдельных микроРНК или их панелей при сердечно-сосудистых заболеваниях.

Об авторах

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