ОСОБЕНОСТИ ИММУНОГЕМАТОЛОГИЧЕСКОЙ ДИАГНОСТИКИ АЛЛОИММУНИЗИРОВАННОГО ПАЦИЕНТА (СЛУЧАЙ ИЗ ПРАКТИКИ)

Аннотация

При проведении обязательного предтрансфузионного скрининга антител и идентификации группы крови системы АВО можно столкнуться с трудностями, обусловленными свойствами некоторых аллоантител. Представлен случай из практики — пример взаимодействия анти-М аллоантител с тест-эритроцитами. Описаны особенности результатов иммуногематологического тестирования пациентов с аллоантителами класса IgM.

Annotation

When carrying out mandatory pre-transfusion antibody screening and identification of the ABO blood group, difficulties may be encountered due to the properties of some alloantibodies. The paper presents a clinical example of the interaction of anti-M alloantibodies with test red blood cells. The features of the results of immunohematological testing of patients with alloantibodies of the IgM class are described.
Key words: red blood cells; antigens; alloantibodies; MNS; antibody identification.

Об авторах

Список литературы

1.https://www.shotuk.org/wp-content/uploads/myimages/SHOT-REPORT-2022-FINAL-Bookmarked.pdf.
2.https://www.shotuk.org/wp-content/uploads/myimages/SHOT-REPORT-2021-FINAL-bookmarked-V3-November.pdf.
3.Butina E.V., Mineeva N.V., Zaytseva G.A., Poponina E.A., Yovdiy A.V. Red blood cell alloimmunization in patients with hematology/oncology disorders. Transfuziologiya. 2019; 20(2): 107-14. (in Russian)
4.Mineeva N.V., Pashkova I.A., Krobinets I.I., Sysoeva E.A. Allosensibilisation to erythrocyte antigens (literature review). Onkogematologiya. 2015; 10 (4): 60-5. (in Russian)
5.Order of the Ministry of Health of the Russian Federation dated October 20, 2020 No. 1134 On approval of the procedure for a medical examination of a recipient, testing for individual compatibility, including a biological sample, during transfusion of donor blood and (or) its components. (in Russian)
6.Yovdiy A.V., Butina E.V., Poponina E.A., Zaytseva G.A., Minaeva N.V. Interpretation of the results of immunohemtological studies in patients of the hematology clinic. Clinical laboratory diagnostics. 2019; 64 (4): 221-4. (in Russian)
7.Pashkova I.A. Algorthms for solving problems of pre-transfusion immunogematological testing. Gematologiya I transfuziologiya. 2019; 64 (2):222-33. (in Russian)

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