Аннотация
Представлены результаты исследования стандартных липидных показателей, липидных индексов и артериального давления у 91 мужчины работоспособного возраста, проживающих в экстремальных условиях Арктической зоны Российской Федерации. В зависимости от возраста все обследуемые распределились на 5 групп (1-я группа – до 29 лет, 2-я группа – 30-39 лет, 3-я группа – 40-49 лет, 4-я группа – 50-59 лет, 5-я группа – 60-69 лет). Мужчины 1-й группы имели нормальные величины артериального давления, индекса массы тема (ИМТ), показатели липидного профиля соответствовали референсным значениям. Однако два липидных индекса (коэффициент атерогенности – КА) и индекс накопления липидов (lipid accumulation product – LAP) оказались повышенными. У мужчин 2-й группы отмечено увеличение ИМТ, окружности талии, отношения окружности талии/окружности бедер, свидетельствующие о формировании абдоминальной формы предожирения. В этой группе были повышены 4 липидных индекса (КА, LAP, холестерин (ХС), не связанный с липопротеинами высокой плотности – ХС-неЛПВП и отношение триглицеридов/ХС-ЛПВП). У мужчин 3-й группы зарегистрировано высокое нормальное давление, признаки абдоминальной формы предожирения, гипертриглицеридемия, максимально высокие липидные индексы, особенно КА, LAP и отношение триглицеридов/ХС-ЛПВП. В 4-й группе на фоне высокого нормального давления и наличия абдоминальной формы предожирения обнаружено увеличение ХС и холестерина липопротеинов низкой плотности (ХС-ЛПНП), тенденция к снижению липидных индексов, кроме ХС-неЛПВП. У мужчин 5-й группы сохраняются высокое нормальное давление и признаки абдоминальной формы предожирения, повышенные липидные индексы. При этом стандартные липидные показатели соответствовали референсным значениям. Показатель ремнантный ХС в 3-й и 5-й группах был выше, чем в 1-й группе. Таким образом, результаты исследования свидетельствуют о целесообразности использования липидных индексов при обследовании северян. Несмотря на отсутствие субъективных ощущений, полезным становится изменение образа жизни (сбалансированное питание, осознанная двигательная активность, соблюдение режима труда и отдыха и др.), которое позволит регулировать массу тела и артериальное давление.
Annotation
The results of the study of standard lipid parameters, lipid indices and blood pressure in 91 men of working age living in extreme conditions of the Arctic zone of the Russian Federation are presented. Depending on the age, all the subjects were divided into 5 groups (1st – up to 29 years, 2nd – 30–39 years, 3rd – 40–49 years, 4th – 50–59 years, 5th – 60–69 years). Men of the 1st group had normal values of blood pressure, body mass index (BMI), lipid profile indicators corresponded to reference values. However, two lipid indices (atherogenicity coefficient – AC) and the lipid accumulation product index (LAP) were elevated. In men of the 2nd group, an increase in BMI, waist circumference, the ratio of waist circumference/hip circumference was noted, indicating the formation of an abdominal form of pre-obesity. In this group, 4 lipid indices were increased (AC, LAP, cholesterol (TC) not associated with high-density lipoproteins – TC-nonHDL and the ratio of triglyceride/HDL-C). In men of group 3rd, high normal blood pressure, signs of abdominal pre-obesity, hypertriglyceridemia, the highest lipid indices, especially AC, LAP and ratio triglyceride/HDL-C, were registered. In group 4th, against the background of high normal pressure and the presence of abdominal pre-obesity, an increase in TC and low-density lipoprotein cholesterol (LDL-C) was found, a tendency to decrease lipid indices, except for HDL-C. Men of the 5th group have high normal blood pressure and signs of abdominal pre-obesity, elevated lipid indices. At the same time, the standard lipid parameters corresponded to the reference values. Thus, the results of the study indicate the expediency of using lipid indices in the examination of Northerners, especially among young people. Despite the absence of subjective feelings, it will be useful to change the lifestyle (balanced diet, conscious motor activity, compliance with work and rest, etc.), which will allow you to regulate body weight and blood pressure.
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